Quantifying how red blood cells deform, adapt, and fail under physiologically relevant mechanical and electrical environments encountered in the microcirculation and medical devices.
Haemocompatibility of Medical Devices
Investigating how blood–device interactions drive blood damage and thrombogenicity, and developing quantitative approaches to improve the safety of blood-contacting medical technologies.
Artificial Blood Cell Surrogates
Engineering mechanistically faithful blood cell surrogates to enable reproducible, ethical, and regulator-relevant haemocompatibility testing without reliance on donor blood.
Microfluidic and Microscale Testing Platforms
Developing physiologically relevant experimental platforms that replicate device-scale flow, stress, and transport conditions to interrogate blood behaviour with high precision.
Blood Damage and Flow-Mediated Thrombosis
Defining the mechanical and hydrodynamic pathways leading to haemolysis, platelet activation, and thrombosis in blood-contacting devices and extracorporeal systems.
Organ Perfusion and Life-Support Technologies
Applying blood biomechanics and haemocompatibility principles to improve the safety, performance, and translational reliability of organ perfusion and life-support systems.
Standards, Regulation, and Translation
Generating mechanistic evidence to inform haemocompatibility standards and support regulatory decision-making for blood-contacting medical devices.
Open-Source Biomedical Instrumentation
Designing accessible, open-source experimental tools to accelerate reproducible research and innovation in blood biomechanics and medical device testing.